37 articles for thisTarget
The following articles (labelled with PubMed ID or TBD) are for your review
PMID
Data
Article Title
Organization
Discovery of small molecule integrin alphavbeta3 antagonists as novel anticancer agents.
University of Southern California
Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery.
University of Southern California
Application of CoMFA and CoMSIA 3D-QSAR and docking studies in optimization of mercaptobenzenesulfonamides as HIV-1 integrase inhibitors.
University of Southern California
Small molecule inhibitors of signal transducer and activator of transcription 3 (Stat3) protein.
University of Southern California
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
University of Southern California
Synthesis, chiral high performance liquid chromatographic resolution and enantiospecific activity of a potent new geranylgeranyl transferase inhibitor, 2-hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic acid.
University of Southern California
Farnesyl pyrophosphate synthase enantiospecificity with a chiral risedronate analog, [6,7-dihydro-5H-cyclopenta[c]pyridin-7-yl(hydroxy)methylene]bis(phosphonic acid) (NE-10501): Synthetic, structural, and modeling studies.
University of Southern California
Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator--a hybrid structure of 17beta-estradiol and vitamin E in hippocampal neurons.
University of Southern California
Structure-based virtual screening for plant-based ERbeta-selective ligands as potential preventative therapy against age-related neurodegenerative diseases.
University of Southern California
Discovery of novel small-molecule inhibitors of human epidermal growth factor receptor-2: combined ligand and target-based approach.
University of Southern California
A highly efficient route to enantiomerically pure l-N-Bz-Pmp(t-Bu)2-OH and incorporation into a peptide-based protein tyrosine phosphatase inhibitor.
University of Southern California
Synthesis and biological evaluation of alpha-halogenated bisphosphonate and phosphonocarboxylate analogues of risedronate.
University of Southern California
Inhibition of HIV-1 integrase activity by synthetic peptides derived from the HIV-1 HXB2 Pol region of the viral genome.
University of Southern California
-Methylpropargylamine-Conjugated Hydroxamic Acids as Dual Inhibitors of Monoamine Oxidase A and Histone Deacetylase for Glioma Treatment.
University of Southern California
Diketo acid pharmacophore. 2. Discovery of structurally diverse inhibitors of HIV-1 integrase.
University of Southern California
GPCR Agonist-to-Antagonist Conversion: Enabling the Design of Nucleoside Functional Switches for the A
University of Southern California
Beta-diketo acid pharmacophore hypothesis. 1. Discovery of a novel class of HIV-1 integrase inhibitors.
University of Southern California
Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I).
University of Southern California
Development of a Potent and Specific FGFR4 Inhibitor for the Treatment of Hepatocellular Carcinoma.
University of Southern California
Rigidification Dramatically Improves Inhibitor Selectivity for RAF Kinases.
University of Southern California
Development of Alkyne-Containing Pyrazolopyrimidines To Overcome Drug Resistance of Bcr-Abl Kinase.
University of Southern California
Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction.
University of Southern California
Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction.
University of Southern California
Discovery of novel inhibitors of LEDGF/p75-IN protein-protein interactions.
University of Southern California
Development of the next generation of HIV-1 integrase inhibitors: pyrazolone as a novel inhibitor scaffold.
University of Southern California
Discovery of 3-acetyl-4-hydroxy-2-pyranone derivatives and their difluoridoborate complexes as a novel class of HIV-1 integrase inhibitors.
University of Southern California
Quinolone 3-carboxylic acid pharmacophore: design of second generation HIV-1 integrase inhibitors.
University of Southern California
Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors.
University of Southern California
Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore.
University of Southern California
Substituted 2-pyrrolinone inhibitors of HIV-1 integrase.
University of Southern California
Effects of rigidity on the selectivity of protein kinase inhibitors.
University of Southern California
In-cell production of a genetically-encoded library based on the ?-defensin RTD-1 using a bacterial expression system.
University of Southern California
Cyclotides, a versatile ultrastable micro-protein scaffold for biotechnological applications.
University of Southern California
Structure-Based Discovery of New Antagonist and Biased Agonist Chemotypes for the Kappa Opioid Receptor.
University of Southern California